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Serum albumin oxidation and inter-alpha-trypsin-inhibitor heavy chain-4 abundance correlates with the dystropathology in the rat model of Duchenne muscular dystrophy.
Duchenne muscular dystrophy (DMD) is a fatal X‑linked genetic disease caused by the absence of functional dystrophin, resulting in muscle membrane fragility, chronic inflammation, and progressive muscle wasting. The lack of effective treatments is further compounded by the slow onset of measurable changes in clinical o...