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C. Klaver

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Review Open access Aug 2026

Monotherapy or combination therapy for myopia control: a structured narrative comparison of 12-month axial elongation

ABSTRACT Purpose: To compare annual axial elongation in children treated with low-dose atropine (0.01%) combined with optical interventions versus higher-dose atropine (≥0.05%) monotherapy and to assess whether combination therapy provides a clinically meaningful advantage over single-agent pharmacologic treatment. Met...

J. Polling, D. V. van Hemert, Hozan Zebari et al. · 0 citations
Open access Aug 2026

The AP5B1 p.Leu785Pro variant is a frequent cause of late-onset macular dystrophy with variable extraocular manifestations

Findings further support AP5B1 as a cause of macular dystrophy, identify p.(Leu785Pro) as a relatively frequent pathogenic allele in individuals of European and Ashkenazi Jewish ancestry, and expand the associated phenotypic spectrum to include both isolated macular dystrophy and possible syndromic presentations.

Petra Liskova, L. Dudakova, Karolina Kaminska et al. · 0 citations

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