Author

C. Lundberg

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Open access Oct 2026

In Vitro and In Vivo Efficacy of the Broad-Spectrum β-Lactamase Inhibitor APC24-7 in Combination with Meropenem Against Carbapenem-Resistant Enterobacterales

Background: Carbapenem-resistant Enterobacterales (CRE) represent a major therapeutic challenge, driven in part by serine β-lactamases (SBLs) and metallo-β-lactamases (MBLs). APC24-7 is a broad-spectrum β-lactamase inhibitor (BLI) designed to inhibit enzymes from both groups. Here, we evaluated the ability of APC24-7 t...

C. Matias, K. S. Jensen, H. Hasman et al. · Antibiotics · 0 citations

Open access Sep 2026

Gallium phosphate nanoparticles as an antibiotic-free strategy against Pseudomonas aeruginosa lung infections.

Rising bacterial resistance and the declining efficacy of existing antibiotics demand new antimicrobial strategies. Gallium ions are analogs of ferric ions and can disrupt bacterial iron homeostasis. However, their effective delivery to infected lungs remains a challenge. Here, we report an antibiotic-free antimicrobia...

Sheng Yu, Yong-Bao Zhuang, Veronica Rondahl et al. · Journal of Colloid and Inter... · 0 citations