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Author

C. Macrea

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Review Open access Aug 2026

The Genetic Landscape of Colorectal Cancer: From Molecular Alterations to Therapeutic Decision Pathways

This review summarizes the most clinically relevant genetic biomarkers currently used in colorectal cancer, including microsatellite instability, RAS and BRAF mutations, HER2 amplification, and NTRK fusions, while also discussing emerging biomarkers such as circulating tumor DNA, tumor mutational burden, transcriptomic...

C. Macrea, Tiberia Ilias, Alexandra Costea et al. · 1 citation

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