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Author

C. McManus

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Open access Aug 2026

Drosophila Rumpelstiltskin regulates Polycomb cis and trans interactions and Homie barrier activity

Three-dimensional genome organization is maintained in part by chromatin insulators, DNA–protein complexes that create boundaries between active and inactive chromatin and regulate enhancer-promoter interactions. In Drosophila, the Homing insulator at eve (Homie) sequence prevents repressive Polycomb (PcG) chromatin at...

Savanna Lyda, C. McManus, Juan Manuel Caravaca et al. · 0 citations

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