Disruption of dnaK results in transcriptional reprogramming of biofilm-associated pathways in Clostridioides difficile
Abstract Introduction. Clostridioides difficile is an opportunistic enteric pathogen posing significant challenges in human and animal healthcare due to the recurrent nature of infections and associated financial burden. The molecular chaperone protein, DnaK (Hsp70), encoded by dnaK, plays a central role in the heat st...