Hyperphosphorylated tau pathology in patients with epilepsy and dementia - Neuropathological insights from a historical autopsy cohort.
Dementia epileptica was associated with increased pTau burden in the epileptogenic hemisphere and time since diagnosis supporting the concept of seizure-induced pTau accumulation, however, pTau is unlikely to be the primary neuropathological link between epilepsy and dementia in the cohort studied given the overall mil...