Author

C. Pan

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Open access Jul 2026

Oncogenic PIK3CA reprograms glutamine metabolism to drive bladder cancer progression.

PIK3CA mutations are frequent drivers of metabolic reprogramming in BLCA, leading to increased glutamine flux, elevated OXPHOS activity, and enhanced fatty acid synthesis, all of which contribute to tumor progression.

K. R. Kami Reddy, V. Putluri, D. Piyarathna et al. · Cell communication and signa... · 0 citations