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Author

C. Pecoraro

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Review Open access Sep 2026

Personalized medicine, scientific revolution or self-serving illusion: viewpoint from EORTC-PAMM Group.

Personalized medicine has redefined oncology by tailoring treatments to molecular and clinical characteristics. However, despite remarkable advances in biomarker discovery and targeted therapy, the integration of pharmacological principles into precision oncology remains limited. The resulting discrepancy between biolo...

V. Debien, A. Géraud-Crémieux, M. Le Grand et al. · 0 citations
Aug 2026

3-amino-1,2,4-triazine scaffolds as next-generation PDK inhibitors: Design, mechanistic insights, and efficacy in pancreatic ductal adenocarcinoma.

Overall, these results identify amino-triazine-based scaffolds as a promising new class of potent and selective PDK inhibitors with significant anticancer potential in pancreatic cancer.

D. Carbone, Cristiano Biancucci, Michele De Franco et al. · 0 citations

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