Incubation of cocaine craving is associated with reduced context-induced Fos expression in parvalbumin interneurons in the nucleus accumbens core of male rats.
Substance use disorder develops in a subset of individuals after repeated drug exposure and is characterized by escalating intake and loss of control over use. Rodent self-administration protocols with varying drug access durations are used to study controlled and compulsive drug use and its neurobiology. Drug-associat...