Sep 2026
Abstract A002: Transcriptional regulation and membrane sequestration of myeloid-derived TNF in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy defined by stromal desmoplasia, inflammation, and an immunosuppressive tumor microenvironment (TME) enriched for innate immune cells and characterized by effector T-cell dysfunction. Beyond malignant epithelial cells, the PDAC TME is composed predominantl...
Andrew Adams, H. Amirian, C. Rafie et al.
· Cancer Research · 0 citations