Open access
Jul 2026
Individual differences in brain cocaine pharmacokinetics predict cocaine intake patterns in rats.
Pharmacokinetic factors play a critical role in cocaine use. Previous work mainly examined externally driven pharmacokinetic manipulations, showing that conditions producing rapid fluctuations in brain cocaine levels, such as intermittent versus continuous access, promote burst-like intake, increased motivation for coc...
D. Conlisk, Gabriela Goncalves Valente, J. Wiart et al.
· Biomedicine & pharmacotherap... · 0 citations