Margin positivity and re-excision after breast-conserving surgery following neoadjuvant chemotherapy: A systematic review and meta-analysis.
Neoadjuvant chemotherapy (NACT) is increasingly used to facilitate breast-conserving surgery (BCS) in patients with early-stage and locally advanced breast cancer. However, tumour response to NACT is heterogeneous, and comparative studies have reported higher rates of margin involvement and re-excision compared with pr...