Open access
Sep 2026
Tannerella forsythia-Porphyromonas gingivalis polymicrobial biofilm synergy boosts host inflammation and remodels the T. forsythia transcriptome
Combined biofilm challenge induced upregulation of 47 genes in human periodontal ligament mesenchymal stromal cells, predominantly within the TNF and NF-κB signaling pathways, far exceeding inflammatory responses elicited by either pathogen alone.
Fabian L. Kendlbacher, Muhammad Afzal, O. Andrukhov et al.
· npj Biofilms and Microbiomes · 0 citations