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Author

C. Schliehe

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Jul 2026

Prime-Target neoantigen vaccination strategy enhances neoantigen-specific T cell immunity at the tumor microenvironment in murine cold tumor models 2256928

A novel “Prime-Target” neoantigen vaccination strategy that combines subcutaneous (SQ) and intra-tumor (IT) neopeptide vaccinations with a potent adjuvant combination of K3 CpG plus c-di-AMP (K3/c-di-AMP) is proposed.

Kou Hioki, Marlous Wildemans, Youkyung Lim et al. · 0 citations
Open access Sep 2026

T cell receptors equipped with ICOS provide T cells with durable anti-tumor response

A novel and uniformly applicable TCR:ICOS format that supports fitter T cell products for adoptive cell therapy and identifies a single amino acid change in the cytosolic tail which enabled functional surface expression without proneness to TCR mispairing nor competition for CD3.

Alexandre Marraffa, C. Berrevoets, Margherita Mosiello et al. · 0 citations

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