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C. Schlötterer

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Open access Oct 2026

Epistatic redundancy reconciles pervasive genetic interactions with their rarity in genome-wide analyses.

Epistasis, the genetic interaction between loci, has long been recognized as a fundamental feature of the genetic architecture, but its importance remains controversial. This controversy stems partly from the apparent disconnect between abundant physiological epistasis observed in laboratory settings and the rarity of...

C. Schlötterer · 0 citations
Open access Aug 2026

A striking mismatch between genomic and phenotypic selection responses– the role of pleiotropy in complex environments

A major focus of evolutionary biology is the characterization of the genetic basis of adaptation. A widely used approach builds on the comparison of allele frequencies among populations adapted to different environments, reasoning that differentiated loci uncover the genetic basis of adaptation. We evolv...

Chang-Yi Xiao, Sara Duarri-Redondo, Yi-Wen Chen et al. · 0 citations

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