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Author

C. Schmidt

2 papers indexed here

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Open access Oct 2026

Integrated single-cell and proteomic profiling of pancreatic neoplasia identifies tissue markers that outperform established diagnostic markers in distinguishing cancer from precursor lesions.

Pancreatic ductal adenocarcinoma (PDAC) arises within an extensively remodeled microenvironment, yet tissue markers that distinguish invasive carcinoma from precursor lesions remain limited. Integrating four single cell RNA sequencing atlases comprising 324,662 cells from 26 patients, we identified cancer associated fi...

T. Tran, P. Nguyễn Hoàng, D. Pham et al. · 0 citations
Open access Aug 2026

A blood-based signature of cytoskeletal and extracellular remodeling for risk stratification of intraductal papillary mucinous neoplasms

Integrated proteomic and spatial transcriptomic datasets of IPMN tissues revealed coordinated alterations cytoskeletal and ECM remodeling and elevated matrix stiffness as prominent features associated with IPMN/PDAC, which paralleled concordant increases in BGN and ITGB1BP1.

L. Patterson, R. Ballarò, Y. Chen et al. · 0 citations

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