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More signal versus more noise: comparing full text and abstract as inputs for large language model-based classification of oncology trial eligibility criteria
Abstract Objectives Large language models (LLMs) offer significant potential for automating clinical trial classification by eligibility criteria. However, the optimal input data remain unclear: while abstracts provide a condensed signal, full-text articles contain substantially more information. Whether this additiona...
Evidence Use and Identifier-Conditioned Prior Knowledge in Large Language Model Classification of Oncology Trials Assessed Through Progressive Content Removal and Counterfactual Testing: Comparative Analysis
Testing whether oncology randomized trial success classification is driven by abstract evidence or by identifier-conditioned prior knowledge, and whether models follow counterfactual outcome evidence when it conflicts with original trial identifiers showed that identifiers can carry predictive signal and occasionally c...