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C. Sticherling

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Open access Sep 2026

COnCOmitaNt pulsed field ablation-based pUlmonary vein isolation and lefT atrial appendage closure: the COCONUT study

Abstract Aims Atrial fibrillation (AF) ablation by pulmonary vein isolation (PVI) and left atrial appendage closure (LAAC) are increasingly performed as standalone procedures. Given that PVI and LAAC share the same access route, a combined approach of pulsed field ablation (PFA)-based PVI and LAAC might be beneficial....

Christian-Hendrick Heeger, Laurent Roten, D. Della Rocca et al. · 0 citations
Open access Aug 2026

Pulmonary Vein Isolation Using Pulsed Field Ablation With vs Without Posterior Wall Isolation in Patients With Symptomatic Persistent Atrial Fibrillation: The PIFPAF-PFA Randomized Clinical Trial.

Importance Pulmonary vein isolation (PVI) is less effective in persistent than in paroxysmal atrial fibrillation (AF). Objective To determine whether adding posterior left atrial wall isolation (PWI) to pulsed field ablation (PFA)-based PVI reduces atrial tachyarrhythmia in patients with persistent AF. Design, Sett...

L. Roten, J. Maurhofer, P. Krisai et al. · 4 citations
Open access Sep 2026

Left atrial anatomy and atrial arrhythmia recurrence after pulsed-field ablation.

BACKGROUND The impact of left atrial (LA) anatomical features on atrial arrhythmia (AA) recurrence after pulsed-field (PF)-based pulmonary vein isolation (PVI) is unknown. This study aimed to assess LA anatomical features associated with long-term AA recurrence after PVI. METHODS We prospectively enrolled patients un...

M. Mutti, D. Spreen, Jonas Brügger et al. · 0 citations
Open access Sep 2026

Safety and Efficacy of Left Atrial Ablation After Percutaneous Left Atrial Appendage Occlusion in High-Bleeding-Risk Patients with Atrial Fibrillation: A Multicenter Analysis from the PROCEED-AF Ablation Registry.

BACKGROUND AND AIMS Patients with left atrial appendage (LAAO) devices are increasingly referred for AF ablation, yet anticoagulation strategies remain uncertain. The goal of this study was to evaluate the safety and efficacy of catheter ablation for atrial fibrillation (AF) in patients with pre-existing LAAO devices a...

Rachel M. Kaplan, J. du Fay de Lavallaz, Christian-Hendrick Heeger et al. · 0 citations
Open access Aug 2026

Undetected Heart Failure in Cardiology: Prevalence, Characteristics, and Outcome.

One-out-of three patients referred for CAD work-up had undetected HF, which was associated with cardiovascular death and AHF hospitalization, and was associated with an increased cumulative incidence of the composite endpoint.

Laurève Chollet, K. Rumora, K. Durak et al. · 0 citations
Review Open access Aug 2026

Prophylactic implantation of implantable cardioverter-defibrillator for the primary prevention of sudden cardiac death after myocardial infarction: protocol for systematic review and meta-analysis of randomised controlled trials

A systematic review and meta-analysis will evaluate and provide primary evidence for the effectiveness of prophylactic implantation of TV-ICDs on all-cause mortality in patients who experienced MI, aiming for primary prevention of SCD after MI.

A. Amarasekera, Anoja W. Gunaratne, J. Kovoor et al. · 0 citations
Open access Aug 2026

Mortality reduction with implanted defibrillator for primary prevention of sudden death after Myocardial Infarction: temporal trends in the PROFID study.

In this analysis including a large cohort of post-myocardial infarction patients with reduced LVEF, the estimated mortality reduction associated with primary prevention ICD implantation progressively decreased over time.

Alireza Sepehri Shamloo, T. Chiba, J. G. Tijssen et al. · 0 citations

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