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Author

C. Tzoulis

2 papers indexed here

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Open access Aug 2026

Neuroinflammation and metabolic dysfunction in POLG-related mitochondrial epilepsy

Super-refractory status epilepticus is a common neurological manifestation of mitochondrial disease caused by bi-allelic pathogenic variants in POLG. Epilepsy in POLG-related disease typically presents with an explosive onset of status epilepticus, often from an occipital focus, and is associated with extensive neurode...

Laura A. Smith, Megan Wilson, Elsaid Mohamed Elsaid et al. · 0 citations
Open access Aug 2026

7 Tesla MRI with Quantitative Susceptibility Mapping: qualitative grading and quantitative focal measurements of the substantia nigra as a potential biomarker for Parkinson's disease.

PURPOSE Parkinson's disease (PD) is characterized by dopaminergic neuronal loss in the substantia nigra (SN). Imaging biomarkers sensitive to nigral pathology are limited. This study evaluated susceptibility changes in the SN using quantitative susceptibility mapping (QSM) and susceptibility-weighted imaging (SWI) at 7...

R. G. Unsgård, K. E. Stige, A. L. Kristoffersen et al. · 0 citations

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