Author

C. V. van Tilburg

2 papers indexed here

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Open access Sep 2026

Interdisciplinary management and genetic evaluation of pediatric cancer predisposition syndromes: a retrospective cohort study.

Comprehensive knowledge of cancer predisposition syndromes (CPS) is essential for the implementation of surveillance programs with proven clinical benefit. An interdisciplinary expert panel was established at our center to facilitate early identification of children with suspected CPS. This retrospective cohort study a...

N. Dikow, Anna-Katharina Nitschke, S. Hirsch et al. · European Journal of Human Ge... · 0 citations

Open access Jul 2026

Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experience

Pediatric solid high-risk malignancies mostly lack established molecular biomarkers for early detection, minimal residual disease assessment, or treatment monitoring. Challenges include small patient numbers, limited sample volumes, low tumor mutational burden, and few recurrent alterations. Within the multicenter pedi...

K. Maass, P. Puranachot, S. Volz et al. · Genome Medicine · 0 citations