MFN1 Mediates Doxorubicin-Induced Cytotoxicity through Oxidative Stress-Induced Ferroptosis
Doxorubicin (DOX)-induced cardiotoxicity (DIC) limits clinical application of DOX, and the mechanism is linked to ferroptosis. Mitofusin 1 (MFN1) has been reported to be involved in regulating cell death and mitochondrial dysfunction, yet its role in DIC remains unclear. In an in vitro DIC model using H9c2 cells,...