Author

C. Wilson

2 papers indexed here

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Open access Sep 2026

Cofilin Suppresses Tau-Induced Defects in Dense-Core Granule Formation and Aβ-Induced Neurodegeneration

Intracellular neurofibrillary tangles formed from hyperphosphorylated tau and extracellular amyloid plaques containing aggregated Aβ-peptides, specific cleavage products of the Amyloid Precursor Protein (APP), are the primary histopathological hallmarks of Alzheimer’s Disease (AD), the leading cause of dementia in huma...

Bhavna Verma, A. Cording, Lewis Blincowe et al. · bioRxiv · 0 citations

Open access Sep 2026

Rab11-exosome biogenesis regulators mediate Aβ-induced intercellular propagation of endolysosomal trafficking defects and neurodegeneration

Alzheimer’s Disease (AD) is characterised by two histopathological hallmarks, intracellular tau-containing neurofibrillary tangles and extracellular amyloid plaques containing β-amyloid (Aβ), a specific cleavage product of Amyloid Precursor Protein (APP). Initiation of Aβ-induced neuronal pathology, however, has been p...

A. Cording, Bhavna Verma, Adam Arous et al. · bioRxiv · 0 citations