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Open access Sep 2026

669. Imaging reward circuitry to guide precision ketamine treatment in treatment-resistant depression

Abstract Background Ketamine produces rapid antidepressant and anti-anhedonic effects in treatment-resistant depression, but response is heterogeneous and mechanisms at the circuit level remain incompletely defined. Convergent imaging work implicates anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (DLPF...

C. Zarate · 0 citations

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