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Author

Camila Garnica-Álvarez

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Review Open access Sep 2026

Global seroprevalence of neutralizing and total antibodies against AAV vectors and their impact on the clinical gene therapy landscape: a scoping review

Pre-existing neutralizing antibodies (NAbs) and total antibodies (TAbs) against adeno-associated virus (AAV) vectors represent a major barrier to the clinical translation of AAV-based gene therapies. A comprehensive characterization of their global prevalence, determinants, and clinical implications is currently lackin...

Cristina Sánchez Gutierrez, Luisa Fernanda Bohorquez-Zambrano, Camila Garnica-Álvarez et al. · 0 citations

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