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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Camille Acevedo

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2 papers indexed here

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Sep 2026

Abstract A006: A p38α MAPK-TCF21 axis regulates pancreatic stellate cell activation and stromal reprogramming in pancreatic cancer

Pancreatic stellate cells (PSCs) are a principal source of cancer-associated fibroblasts (CAF) in pancreatic ductal adenocarcinoma (PDAC), yet the mechanisms that convert tumor-derived inflammatory cues into a persistent, CAF-like state remain poorly defined. We previously identified tumor cell-intrinsic p38α MAP...

Sayan Chakraborty, Camille Acevedo, Samara P. Singh et al. · 0 citations
Sep 2026

Abstract B001: Cancer-associated fibroblast p38α MAPK signaling coordinates collagen architecture and immune suppression to drive chemoresistance in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) remains highly refractory to chemoimmunotherapy due in large part to its dense, immunosuppressive stroma. Cancer-associated fibroblasts (CAFs), the dominant stromal cell population, promote tumor progression through inflammatory signaling, aligned collagen-rich extracellula...

Camille Acevedo, Sayan Chakraborty, Samara P. Singh et al. · 0 citations

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