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Author

Camilo Perez

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Open access 2026

Design and Optimization of BRIL Fusion Constructs for Membrane Protein Cryo-EM Studies.

Structural determination of small membrane proteins by cryo-electron microscopy (cryo-EM) remains inherently challenging due to their low molecular weight, conformational heterogeneity, and lack of prominent structural features for reliable particle alignment. In this chapter, we describe how to design and perform biop...

Amrutha H. Chidananda, Camilo Perez · 0 citations
2026

Mass Photometry Analysis of Membrane Proteins in Detergent Micelles.

This chapter presents a modification of the basic mass photometry workflow that enables the analysis of membrane proteins in the presence of detergents, which are essential for maintaining the stability of these proteins in solution but often introduce significant artifacts and noise.

Nil Cortiella-Valls, Eric Cester, Camilo Perez · 0 citations

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