Author

Can-Gui Wu

2 papers indexed here

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Open access Oct 2026

Integrated CDK4/6 inhibitor resistance and primary-metastatic discordance in hormone receptor-positive/HER2-negative metastatic breast cancer: a translational framework focused on invasive ductal carcinoma with gastric metastasis

CDK4/6 inhibitors have reshaped treatment for hormone receptor-positive (HR+)/HER2-negative metastatic breast cancer, but resistance frequently emerges and may interact with metastatic phenotypic evolution. We developed an integrated resistance-discordance framework and explored its clinical interpretability in inv...

M. Cheng, Dong-Qing Wang, Ying-Yi Lin et al. · Frontiers in Oncology · 0 citations

Review Open access Sep 2026

Risk of neoplasms with semaglutide in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials

Background Semaglutide is prescribed in conjunction with diet and exercise to improve glycemic control in adults with type 2 diabetes (T2DM). However, its potential impact on tumorigenesis has prompted considerable debate. Methods The meta-analysis was conducted in accordance with PRISMA 2020 guidelines. We searched We...

Yuan-Yuan Zhong, Xing Tan, Ling Zhang et al. · Frontiers in Pharmacology · 0 citations