Open access
Sep 2026
The MAZ-POLD1 Signaling Axis Drives Cisplatin Resistance in Bladder Cancer by Activating DNA Damage Repair
Simple Summary Cisplatin resistance severely limits therapeutic benefits for bladder cancer patients. In this study, we first verified that POLD1 was markedly overexpressed in cisplatin-resistant BC tissues and cells. Functional assays demonstrated that POLD1 knockdown remarkably impaired DDR capacity in cisplatin-resi...
Biao Zhang, Hong Chang, Cheng Wang et al.
· Cancers · 0 citations