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Author

Carla Calvó-Tusell

1 paper indexed here

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Open access Sep 2026

Dimerization and Ligand Binding Rewire Allosteric Networks in SARS-CoV-2 Main Protease.

The SARS-CoV-2 main protease (MPro) is an essential enzyme for viral replication and a primary target for antiviral drug development. Despite extensive structural and biochemical characterization, the allosteric mechanisms by which dimerization informs conformational changes at active site lack an explicit comparison a...

Javier O. Sanlley Hernandez, Carla Calvó-Tusell, Fiona L. Kearns et al. · 0 citations

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