Yeast-Based High-Throughput Screening Platform for Identifying Modulators of Mitochondrial Protein Import.
Mitochondrial protein import is essential for overall cellular homeostasis, yet scalable approaches to systematically interrogate mitochondrial protein import and identify modulators of this process remain limited. Here, we describe a yeast-based, gain-of-growth (GoG), high-throughput screening assay for the identifica...