Rimonabant reveals reward- and anxiety-related behavioral effects of N-arachidonoyl dopamine (N-ADA) in mice.
The endovanilloid N-arachidonoyl dopamine (N-ADA) is a lipid mediator associated with nociception and inflammation, but its effects on reward and anxiety remain unclear. We examined the behavioral impact of subacute N-ADA pre-exposure on conditioned place preference (CPP) and anxiety-like behavior in the circular open-...