Author

Carmem C. Gottfried

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Review Open access Sep 2026

Mechanistic evidence on biological pathways affected by valproic acid: A systematic review.

Valproic acid (VPA) is a widely used medication for the treatment of epilepsy, migraines, neuropathic pain, and mood disorders, with contrasting implications across the lifespan. Prenatal exposure is associated with neurodevelopmental risk, whereas postnatal use has established therapeutic benefits. This systematic rev...

Isabela Drehmer, A. D. Dos Santos, Raul Izidoro Carneiro et al. · Biomedicine & pharmacotherap... · 0 citations

Open access Aug 2026

Autism-specific spliceosomal transcriptomic signatures in prefrontal cortex contrasted with bipolar disorder.

These results support transcriptomic divergence in the prefrontal cortex, with ASD characterized by spliceosomal dysregulation, contrasting with metal ion response, vascular regulation and inflammation-associated signals in BD.

Pedro Marmontel, F. D. Rabelo-da-Ponte, F. Kapczinski et al. · Trends in Psychiatry and Psy... · 0 citations