Carmen Jerónimo

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

High‐risk non‐muscle invasive bladder cancer (NMIBC) is a common urological malignancy with a high propensity for recurrence (30–40% of patients) despite treatment with Bacillus Calmette–Guérin (BCG) instillations. Identifying patients who are likely to respond or not to BCG therapy before treatment initiation may sign...

Assessment of EGFR and HER2 expression in penile cancer as potential therapeutic targets.

Penile cancer (PC) is a rare but aggressive malignancy with limited systemic treatment options, particularly in advanced stages. Targeted therapies against receptor tyrosine kinases such as EGFR and HER2 have demonstrated clinical benefit in other cancer types, yet their role in PC remains poorly defined. Understanding...

Influence of RNA Modifications on Cancer Metabolism: Interplay with Hypoxia and Therapeutic Implications.