Author

Carolina Cardoso Gonçalves

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Open access Aug 2026

A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes

A reproducible human three-dimensional brain tissue model with neurons, astrocytes and microglia, replicating in-vivo-like maturation and enabling the study of Alzheimer’s disease-relevant perturbations and drug responses is developed.

Julien Klimmt, Carolina Cardoso Gonçalves, J. V. Montgomery et al. · Nature Neuroscience · 1 citation