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Author

Caroline E Zielinski

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Jul 2026

MEX3B as a Potent Regulator of Inflammasome Signaling 2267250

Deletion of MEX3B inhibited caspase-4 and gasdermin D activation, pyroptosis, and secretion of inflammasome-dependent inflammatory cytokines in human cell lines and murine primary macrophages and suggested that MEX3B is a pan-inflammasome regulator targeting inflammatory caspases.

Penghua Wang, Jason G. Cahoon, Duomeng Yang et al. · 0 citations