Cellular Prion Protein as a Novel Regulator of Vascular Plexus Stability During Retinal Angiogenesis
Angiogenesis is essential not only during embryogenesis but also in adult physiology and disease, relying on vascular endothelial growth factor (VEGF) gradients to guide tip cell sprouting. Cellular prion protein (PrPC), expressed in several neurovascular unit (NVU) cell types, regulates neuronal and astrocytic differe...