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Author

Catherine Moali

2 papers indexed here

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Open access Oct 2026

Inhibition of endogenous TGF-β normalizes extracellular matrix deposition in hiPSC-derived fibroblasts

Fibroblasts are mesenchymal cells with essential functions for connective tissue homeostasis and repair through the production and organization of the extracellular matrix (ECM). Most reconstructed skin models used in research and skin-related applications rely on fibroblasts to produce ECM. Despite their shared func...

L. Guillot, L. Jobeili, Léa Cassulino et al. · 0 citations
Open access Sep 2026

Structure of PCPE-2 in complex with the BMP-1 metalloprotease reveals the molecular basis of its mechanism of inhibition

PCPE-2 (procollagen C-proteinase enhancer-2) is an extracellular glycoprotein playing dual functions in the regulation of BMP-1/tolloid-like proteinases. Like its homologue PCPE-1, PCPE-2 can enhance the proteolytic maturation of fibrillar procollagens, but it also acts as a potent and specific inhibitor of BMP-1 throu...

Julien Bauer, Priscillia Lagoutte, J. Vaneyck et al. · 0 citations

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