Author

Cecilia Becattini

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Review Sep 2026

Safety of Age-Adjusted and Clinical Probability-Adjusted D-dimer Cut-offs in Suspected Pulmonary Embolism: A Systematic Review and Meta-Analysis.

BACKGROUND Adaptive D-dimer strategies for rule out of pulmonary embolism (PE) have been proposed to improve the efficiency of conventional fixed '500' D-dimer thresholds. Validations of adaptive D-dimer strategies post-hoc in cohorts managed according to the fixed D-dimer threshold seems to questions their safety. Res...

Mara Graziani, B. Akerboom, Y. Freund et al. · Chest · 1 citation

Sep 2026

Central embolic localization in acute pulmonary embolism: Prognostic marker or target for intervention?

BACKGROUND In patients with acute pulmonary embolism (PE), computed tomography pulmonary angiography (CTPA) enables both diagnosis and prognosis. This analysis of symptomatic acute PE patients aims to describe clinical features, management, and short-term outcomes by embolic localization, and to assess the prognostic v...

M. Vedovati, L. Cimini, I. Enea et al. · European journal of internal... · 0 citations

Review Open access Aug 2026

Risk-of-bias assessment in prognostic cohort studies: a methodological comparison study of structured appraisal tools in acute pulmonary embolism research

Structured tools for risk-of-bias assessment in prognostic cohort studies have variable reliability and limited agreement with expert appraisal, whereas ROBINS-I showed the strongest concordance with expert judgement, whereas QUIPS may provide optimistic ratings.

L. Cimini, F. Klok, M. Carrier et al. · BMJ Open · 0 citations