Cem Doğan

Investigation of the Effects of Switching from Bosentan to Macitentan in Pediatric Pulmonary Hypertension Patients

Objectives Pulmonary arterial hypertension (PAH) is a progressive disease characterized by increased pulmonary vascular resistance and reduced exercise capacity. Bosentan, an endothelin receptor antagonist, is commonly used in pediatric PAH, but standardized guidelines for its use are lacking. Macitentan, another endot...