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Author

Chad A. Galloway

1 paper indexed here

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Aug 2026

A 3D human retina model reveals a non-cell-autonomous and non-neuronal mechanism of photoreceptor loss in a lysosomal storage disorder.

Treatment with recombinant human acid ceramidase (rhAC) ameliorated photoreceptor degeneration in both the CLN3 disease RO-RPE model and CLN3 miniswine eyes, suggesting that rhAC could be a therapeutic approach for retinal degeneration in CLN3 disease.

Jimin Han, Nathaniel Foley, Sonal Dalvi et al. · 0 citations

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