Exploring the Potential of Quinoline-Containing Pyrazoline Derivatives as Antidepressant Agents: In Vivo and In Silico Studies.
INTRODUCTION/OBJECTIVE Depression is a common mental disorder, affecting over 300 million people worldwide. Currently available treatments, such as SSRIs, SNRIs, TCAs, and MAOIs, have limited effectiveness and cause side effects. The pharmacological potential of compounds based on diverse novel heterocyclic scaffolds,...