Author

Chaiyaboot Ariyachet

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Open access Sep 2026

Zfp469 Deletion Attenuates Liver Fibrosis by Suppressing Extracellular Matrix Production in Hepatic Stellate Cells.

BACKGROUND Liver fibrosis is driven by excessive extracellular matrix (ECM) deposition following chronic injury. Mutations in the human zinc finger protein 469 (ZNF469) cause Brittle Cornea Syndrome, a systemic connective tissue disorder, yet its functional role in hepatic fibrogenesis remains unexplored in vivo. This...

Nantawat Satthawiwat, Archittapon Nokkeaw, Bootsakorn Boonkaew et al. · Biomedical Journal · 0 citations

Review Sep 2026

Generation of eight-cell embryo-like cells from human pluripotent stem cells.

The approach provides a valuable model for studying human early embryogenesis, particularly the molecular events surrounding ZGA, and is expected that an individual with ~1 year of experience working with human PSC culture would be able to carry out this protocol.

Md. Abdul Mazid, Yun-Pan Li, Min-Die Zhao et al. · Nature Protocols · 0 citations

Review Open access Aug 2026

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Current advances in understanding transcriptional regulatory networks governing fibroblast activation were summarized, with a primary focus on HSCs while highlighting shared mechanisms across multiple fibrotic organs.

Denita Charoenthanakitkul, Chaiyaboot Ariyachet · International Journal of Mol... · 0 citations