Chanaka A. Rabel

Developmental and transcriptomic alterations in bovine blastocysts derived from oocytes of donors exposed to toxic tall fescue.

Fescue toxicosis, caused by the ingestion of ergot alkaloids present in endophyte-infected tall fescue (E + ), is associated with impaired reproductive performance in beef cattle. Because early embryonic development depends on maternally derived RNAs and proteins accumulated during oocyte maturation, disruption of oocy...