Review
Open access
Aug 2026
Targeting pyroptosis for skeletal muscle atrophy: mechanistic insights and therapeutic perspectives
This review systematically elucidates the core molecular mechanisms of pyroptosis, revealing its role in exacerbating skeletal muscle atrophy through direct damage to myofibres and the establishment of chronic inflammatory microenvironments.
Chen-Chen Sun, Tian-Jiao Peng, Peng Zhang et al.
· Frontiers in Immunology · 0 citations