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Chang-Han D. Lee

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Open access Aug 2026

MOTS-c is a mitochondrial-encoded interferon-linked host defense peptide

It is demonstrated that MOTS-c (mitochondrial open reading frame from the 12 S rRNA type-c) is a mitochondrial-encoded amphipathic and cationic peptide with direct antibacterial and immunomodulatory functions, consistent with the peptide chemistry and functions of known HDPs.

Michelle C. Rice, M. Imun, Sang-Wun Jung et al. · 0 citations

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