Author

Chang He

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Open access Sep 2026

A Generalizable Multimodal Model for Treatment‐Stratified Risk and Survival Assessment under Real‐World Constraints: A Multi‐Center Study of Colorectal Cancer

ABSTRACT Integrating histopathology, genomic, and clinical phenotypes holds promise for improving prognostic patient stratification, including within treatment‐defined subgroups, in colorectal cancer (CRC). However, ensuring the availability of all modalities in routine clinical practice remains challenging. Comprehens...

Chuang-Jie Cao, Zhe-Yi Ji, Chang He et al. · Advancement of science · 0 citations

Review Aug 2026

AI-powered medicinal chemistry and translational drug development.

This review examines how machine learning, deep learning, natural language processing (NLP), and generative modeling are being applied across medicinal chemistry and drug development, and highlights how multimodal data fusion, predictive modeling, and human-AI collaborative frameworks are supporting more informed decis...

Kaicheng U, Sophia Meixuan Zhang, Ziyu Yu et al. · Chemical Society Reviews · 0 citations