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Author

Chang-Jiang Qin

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Review Open access Oct 2026

Colitis-associated colorectal carcinogenesis: molecular mechanisms and therapeutic potential

Chronic colitis is a major risk factor for colorectal cancer (CRC), particularly for colitis-associated colorectal cancer (CAC), where persistent inflammation drives the transition from mucosal injury to malignant transformation. Accumulating evidence indicates that gut microbiota dysbiosis, epithelial barrier disrupti...

Yi Lu, Xi-Xi Wang, Cui-Ke Yin et al. · 0 citations
Open access Jul 2026

A lactylation-related transcriptional signature as candidate biomarkers for the early detection of polycystic ovary syndrome: an integrated genomic analysis

Lactylation-related transcriptional signatures may serve as potential candidate biomarkers for the early detection of PCOS, and future studies should validate these biomarkers in larger clinical cohorts, primary granulosa cells, and through direct lactylation or proteomic assays.

Ruichao Wei, Hao Zhang, Wenting Xu et al. · 0 citations

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