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Simple Summary Pseudorabies virus (PRV) is an important swine pathogen that can also infect a broad range of non-porcine mammals. In this study, five PRV genes, UL21, UL24, UL50, UL56, and gG, were individually disrupted in the same PRV JM genetic background using CRISPR/Cas9, and the resulting viruses were comparative...
ABSTRACT African swine fever (ASF), caused by the African swine fever virus (ASFV), remains one of the most devastating transboundary animal diseases worldwide, with case fatality rates reaching up to 100% in acute infections. Viral entry represents the first essential step in infection and is an ideal target for the d...
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