Open access
Sep 2026
Ketone ester alleviates sepsis-associated liver injury through β-hydroxybutyrylation of STAT1.
Sepsis-associated liver injury is characterized by excessive inflammation and macrophage activation. β-Hydroxybutyrate (β-OHB) has anti-inflammatory effects and induces lysine β-hydroxybutyrylation (Kbhb), but the role of site-specific Kbhb in septic liver injury remains unclear. This study examined the role of STAT1 K...
Ya-Ping Bai, Kai Li, Dan Zhu et al.
· Immunobiology · 0 citations